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2018 Mar 15;464:65-74

(2025) Functionally enriched epigenetic clocks reveal tissue-specific discordant aging patterns in individuals with cancer

In physician-supervised protocols, the oral route makes it particularly applicable for leaky gut, IBS, post-surgical GI recovery, and gut-related inflammatory conditions

Under moderate oxidative stress, Keap1 is inhibited, allowing Nrf2 to be translocated to the nucleus, where it acts as an antioxidant